Figure 4. The clinical relevance of SPI1, PRIC285, S1PR4 methylation and correlation with expression in GC by TCGA database.

The promoter methylation status (A, B, C) and RNA expression levels (D) of SPI1, PRIC285 and S1PR4 genes in TCGA public genome database of 29 normal and 230 GC subjects, which were divided into four subtypes (EBV: Epstein–Barr virus-positive; MSI: microsatellite instability high status; GS: genomically stable; CIN: chromosomal instability).