Table 1. Correlation among the expressions of MDM2 and EMT markers (E-cadherin, N-cadherin, Vimentin) in human breast cancer [n (%)].
EMT markers | n | MDM2 expression | Spearman correlation | ||
---|---|---|---|---|---|
negative | positive | value(r) | P value | ||
E-cadherin | |||||
negative | 18 | 2 (11.1) | 16 (88.9) | −0.518 | 0.000 |
positive | 44 | 30 (68.2) | 14 (31.8) | ||
N-cadherin | |||||
negative | 57 | 32 (56.1) | 25 (43.9) | 0.306 | 0.016 |
positive | 5 | 0 (0.0) | 5 (100.0) | ||
Vimentin | |||||
negative | 42 | 27 (64.3) | 15 (35.7) | 0.367 | 0.003 |
positive | 20 | 5 (25.0) | 15 (75.0) |
The spearman correlation was used to compare the degrees of correlation. Positive numbers reflect direct correlation, and negative numbers reflect inverse correlation.