Table 5. Kaplan-Meier univariate analysis of patients with PFH.
| Variable | n | 5-Year survival rate (%) | P value |
|---|---|---|---|
| Sex | 0.540 | ||
| Male | 259 | 57.1 | |
| Female | 123 | 65.8 | |
| Age (yr) | 0.380 | ||
| <60 | 242 | 60.7 | |
| ≥60 | 140 | 58.9 | |
| Tumor size (cm) | <0.001 | ||
| <5 | 267 | 67.9 | |
| ≥5 | 115 | 41.3 | |
| Histological type | 0.160 | ||
| Differentiated | 76 | 65.9 | |
| Undifferentiated | 306 | 57.9 | |
| Tumor location | <0.001 | ||
| Upper third | 97 | 50.3 | |
| Middle third | 67 | 61.9 | |
| Lower third | 192 | 68.5 | |
| Two-third or more | 26 | 23.1 | |
| Borrmann type | <0.001 | ||
| 0 | 88 | 91.4 | |
| I | 3 | 0.0 | |
| II | 93 | 63.9 | |
| III | 180 | 44.7 | |
| IV | 18 | 33.3 | |
| Vascular tumor emboli | <0.001 | ||
| Yes | 137 | 37.6 | |
| No | 245 | 71.5 | |
| Nervous invasion | <0.001 | ||
| Yes | 151 | 41.9 | |
| No | 231 | 71.2 | |
| Pathological stage | <0.001 | ||
| IA | 73 | 93.8 | |
| IB | 47 | 88.8 | |
| IIA | 37 | 73.3 | |
| IIB | 51 | 60.8 | |
| IIIA | 47 | 58.7 | |
| IIIB | 48 | 41.7 | |
| IIIC | 79 | 13.8 | |
| Smoking | 0.833 | ||
| Yes | 70 | 57.3 | |
| No | 312 | 60.1 | |
| Drinking | 0.819 | ||
| Yes | 41 | 58.5 | |
| No | 341 | 59.9 | |
| P21 expression | 0.041 | ||
| Positive | 219 | 54.9 | |
| Negative | 163 | 66.8 | |
| P53 expression | 0.535 | ||
| Positive | 279 | 61.1 | |
| Negative | 103 | 55.8 | |
| c-myc expression | 0.017 | ||
| Positive | 229 | 54.8 | |
| Negative | 153 | 66.8 | |
| EGFR expression | 0.196 | ||
| Positive | 132 | 53.0 | |
| Negative | 250 | 63.3 | |
| Neu/Her-2 | 0.545 | ||
| Positive | 4 | 50.0 | |
| Negative | 378 | 60.1 |