Table 1.
Characteristics and VLDL Kinetics of Subjects with Obesity Who Had Low and High VLDL-TG Concentrations
| Characteristic | VLDL-TG Concentration ≤ 0.60mm (n = 76) | VLDL-TG Concentration > 0.60mm (n = 79) |
|---|---|---|
| VLDL-TG concentration, mm | 0.37 ± 0.02 | 1.09 ± 0.04 |
| Sex, n (%) | ||
| Men | 17 (22%) | 33 (42%) |
| Women | 59 (78%) | 46 (58%) |
| Race, n (%) | ||
| Caucasians | 48 (63%) | 70 (88%) |
| African American | 26 (34%) | 7 (9%)a |
| Other | 2 (3%) | 2 (3%) |
| Age, y | 38 ± 1 | 39 ± 1 |
| Body mass index, kg/m2 | 36.1 ± 0.5 | 36.3 ± 0.4 |
| Body fat, % body weight | 43 ± 1 | 41 ± 1 |
| Intrahepatic TG content, % | 10 ± 1 | 18 ± 1a |
| Intra-abdominal adipose tissue volume, cm3 | 1381 ± 82 | 1964 ± 137a |
| Insulin, mU/L | 14 ± 1 | 17 ± 1 |
| HDL-cholesterol concentration, mg/dL | 46 ± 1 | 40 ± 1a |
| Free fatty acid concentration, μM | 449 ± 15 | 444 ± 17 |
| Free fatty acid Ra, μmol/min | 355 ± 13 | 392 ± 13 |
| VLDL-TG secretion rate, μmol/min | 12.9 ± 0.8 | 21.5 ± 0.9a |
| VLDL-TG FTR, pools/h | 0.70 ± 0.04 | 0.37 ± 0.02a |
| VLDL-TG MRT, min | 102 ± 5 | 184 ± 7a |
| VLDL-TG secretion IRI | 211 ± 26 | 356 ± 31a |
| FFA Ra secreted as VLDL-TG, % | 6.4 ± 0.3 | 8.7 ± 0.5a |
| VLDL-TG:VLDLapoB-100 secretion rate ratio | 10 348 (7732; 13 726) | 12 442 (9726; 17 579) |
Data are means ± sem or medians (quartiles). Values in bold indicate significant difference between groups.
a
Values significantly different between groups after Bonferroni correction for multiple comparisons; P < .05.