Table 3.
Association Between SCFA Concentrations and Phyla and Genera
| Acetate (uM/liter) | Propionate (uM/liter) | Butyrate (uM/liter) | |
|---|---|---|---|
| Phylum | |||
| Firmicutes/Bacteroidetes | r = 0.419, r2 = 0.176, P = .001 | r = 0.215, r2 = 0.046, P = .090 | r = 0.182, r2 = 0.033, P = .134 |
| Bacteroidetes (%) | r = 0.395, r2 = 0.156, P = .001 | r = 0.215, r2 = 0.046, P = .090 | r = 0.173, r2 = 0.030, P = .157 |
| Actinobacteria (%) | r = 0.235, r2 = 0.055, P = .137 | r = 0.216, r2 = 0.047, P = .220 | r = 0.170, r2 = 0.029, P = .310 |
| Genus | |||
| Actinomyces (%) | r = 0.546, r2 = 0.298, P < .001 | r = 0.308, r2 = 0.095, P = .018 | r = 0.271, r2 = 0.073, P = .037 |
| Odoribacter (%) | r = 0.518, r2 = 0.268, P < .001 | r = 0.381, r2 = 0.145, P = .004 | r = 0.370, r2 = 0.137, P = .005 |
| Oscillospira (%) | r = 0.283, r2 = 0.080, P = 0.03 | r = 0.104, r2 = 0.011, P = 0.582 | r = 0.087, r2 = −0.008, P = 0.569 |
| Bifidobacterium (%) | r = 0.187, r2 = 0.035, P = .217 | r = 0.183, r2 = 0.034, P = .317 | r = 0.146, r2 = 0.021, P = .474 |
| Streptococcus (%) | r = 0.458, r2 = 0.210, P < .001 | r = 0.277, r2 = 0.077, P = .065 | r = 0.269, r2 = 0.073, P = .068 |
| Bacteroides (%) | r = 0.456, r2 = 0.208, P < .001 | r = 0.372, r2 = 0.139, P = .009 | r = 0.345, r2 = 0.119, P = .016 |
| Faecalibacterium (%) | r = 0.371, r2 = 0.138, P = .001 | r = 0.372, r2 = 0.138, P = .002 | r = 0.350, r2 = 0.123, P = .003 |
| Blautia (%) | r = 0.388, r2 = 0.151, P = .001 | r = 0.198, r2 = 0.039, P = .098 | r = 0.210, r2 = 0.044, P = .078 |
| Total body fat and fat depots | |||
| Total body fat (%) | r = 0.283, r2 = 0.080, P = .004 | r = 0.534, r2 = 0.285, P < .001 | r = 0.555, r2 = 0.308, P < .001 |
| Visceral fat (cm2) | r = 0.329, r2 = 0.108, P = .002 | r = 0.496, r2 = 0.246, P < .001 | r = 0.455, r2 = 0.207, P < .001 |
| SC fat (cm2) | r = 0.397, r2 = 0.157, P = .001 | r = 0.571, r2 = 0.326, P < .001 | r = 0.539, r2 = 0.290, P < .001 |
| Hepatic fat content (%) | r = 0.031, r2 = 0.001, P = .611 | r = 0.200, r2 = 0.040, P = .075 | r = 0.261, r2 = 0.068, P = .019 |
A general linear model was used to assess the studied associations and age, gender, and ethnicity were used as covariates. The r was calculated by using a Pearson correlation. Eighty-four subjects were analyzed. Statistically significant P values are indicated in bold.