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. 2016 Oct 27;7:13257. doi: 10.1038/ncomms13257

Figure 4. CD1b–GMM plasticity upon GEM TCR engagement.

Figure 4

(a) Superposition of the GEM42 TCR free (blue) and bound to CD1b–GMM (pink) structures. (b–d) Superposition of the binary CD1b–GMM (green) and bound to GEM42 TCR (orange). GMM is represented as stick, and CD1b in cartoon format, while the sphere represents the Cα atom of the glycine 153 residue. The orange and green colours highlight the segment of the CD1b molecule that change conformation upon binding of the GEM42 TCR, namely residues 147–154 of the α2-helix (b,c) and the aromatic residues of the F′-pocket Tyr151, Phe144, Phe88 and Phe84 (d).