Table 4.
Correlation between the BLAF and serum levels of Hsp90-beta and clinicopathologic factors of lung cancer patients
| Groups | N | BALF level of Hsp90-beta | Serum level of Hsp90-beta | ||||||
|---|---|---|---|---|---|---|---|---|---|
|
|
|
||||||||
| M±SD (ng/ml) | df | Statistical value | P | M±SD (ng/ml) | df | Statistical value | P | ||
| Resource | |||||||||
| Benign | 41 | 0.27±0.03 | 125 | T=15.51 | <0.05 | 0.36±0.02 | 125 | T=21.3 | <0.05 |
| Lung cancer | 86 | 0.98±0.02● | 1.63±0.03● | ||||||
| Histology | |||||||||
| LAC | 28 | 0.98±0.23 | 2 | F=3.876 | 0.06 | 1.58±0.2 | 2 | F=0.92 | 0.40 |
| LSCC | 46 | 0.93±0.27 | 1.63±0.44 | ||||||
| SCLC | 12 | 1.14±0.07 | 1.74±0.08 | ||||||
| Pathologic grade | |||||||||
| Undifferentiated | 12 | 1.14±0.08▲ | 3 | F=38.88 | <0.05 | 1.74±0.08▲ | 3 | F=21.77 | <0.05 |
| Poorly | 34 | 1.11±0.13▲ | 1.84±0.35▲ | ||||||
| Moderate | 24 | 0.95±0.13 | 1.55±0.13 | ||||||
| Well | 16 | 0.62±0.24 | 1.22±0.14 | ||||||
| Lymphatic invasion | |||||||||
| N0 | 23 | 0.69±0.25 | 2 | F=48.49 | <0.05 | 1.32±0.36 | 2 | F=21.53 | <0.05 |
| N1-N3 | 53 | 1.07±0.13▲▲ | 1.77±0.26▲▲ | ||||||
| Unavailable | 10 | 1.02±0.19▲▲ | 1.74±0.06▲▲ | ||||||
| TNM stage | |||||||||
| I-II | 21 | 0.67±0.24 | 2 | F=44.38 | <0.05 | 1.26±0.14 | 2 | ||
| III-IV | 53 | 1.06±0.15★ | 1.75±0.31★ | F=22.25 | <0.05 | ||||
| Unavailable | 12 | 1.03±0.17★ | 1.73±0.07★ | ||||||
BALF, bronchoalveolar lavage fluid; LAC, adenocarcinoma of the lung; LSCC, squamous cell carcinoma of the lung; SCLC, small cell lung cancer;
●
cancerous compared with benign and non-cancerous;
▲
undifferentiated and poorly compared with moderate and well;
▲▲
N1-N3 compared with N0;
★
III-IV compared with I-II;
M±SD, mean±standard deviation; df, degree of freedom.