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. 2016 Sep 12;291(45):23490–23505. doi: 10.1074/jbc.M116.756973

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© 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 8. — Transcriptomics analysis of cRyr2Δ50 hearts. A, biological Gene Ontology (PANTHER) groups of significantly changed genes in the cRyr2Δ50 heart transcriptome. B–G, changes in the mRNA levels of Ryr2 (B), as well as other genes involved in excitation-contraction (C), contractility (D), energetics (E), biosynthetic pathways (F), and extracellular matrix (G) (n = 4, *, p ≤ 0.05). All data were plotted as mean ± S.E. Control = Ryr2^{flox/wildtype} + tamoxifen; cRyr2Δ50: Ryr2^{flox/wildtype} × Mhy6-MerCreMer⁺ + tamoxifen.