FIGURE 4.

Increased CD36 expression is associated with M2 polarization and enhanced phagocytosis. A, CD36 and LAL mRNA levels in brain homogenates and correlation between CD36 and LAL gene expression in the brain 7d post-stroke. B, phagocytosis in isolated brain immune cells at 7d post-stroke. Immune cells incubated with fluorescent beads at 4 °C were used as a negative control. The phagocytic activity is expressed as a phagocytosis index calculated by [number of fluorescent⁺ cells]×[mean fluorescence intensity]. n = 11/group. C, brain immune cells were isolated from the brain and divided into two. A phagocytic assay was performed in cells, and CD36 Western blotting was performed in immune cell lysate (1 μg). *, p < 0.05. C, Contra; I, Ipsi.