FIGURE 5.
Inhibition of CD36 reduces phagocytosis in mononuclear phagocytes. A, effect of anti-CD36 antibody on phagocytosis in mouse peritoneal macrophages (n = 7–8/dose). B, effect of SAB on phagocytosis in mouse peritoneal macrophages (n = 20/dose). C, visualization of phagocytosis in vehicle-treated (0 μm) and 200 μm SAB-treated peritoneal macrophages. D, effect of SAB on brain immune cells isolated from ipsilateral hemispheres of 7d post-stroke mice (n = 5–10/dose). One-way ANOVA Bonferroni correction. *, p < 0.05; **, p < 0.01; ***, p < 0.001 versus 0 μg/ml anti-CD36 antibody or 0 μm SAB.