TLR agonists impact on TLR2 expression in splenic Ly6Chi monocytes in the early stage of T. cruzi infection.
A, effect of TLR2 (Pam3Cys, 1 μg/ml) and TLR9 (CpG DNA, 1 μg/ml) agonists on the TLR2 expression in monocytes from 7 days infected WT mice after culture for 10 h. B, effect of TLR9 deficiency on the TLR2 expression in monocytes in the same conditions. The data represent three independent experiments (means ± S.D. of four animals). *, p < 0.05; **, p < 0.01; ***, p < 0.001 by the ANOVA and Bonferroni post-test.