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. 2016 Nov;57(11):1817–1822. doi: 10.2967/jnumed.116.173245

FIGURE 2.

FIGURE 2.

Dose-dependent blocking of 18F-FNDP (3.7 MBq [0.1 mCi]) uptake with sEH inhibitor nor-fluoro-FNDP (s.c. [subcutaneously]) in CD-1 mouse brain at 60 min after radiotracer injection. Data are mean %ID/g tissue ± SD (n = 3). Blocking curve demonstrates that 18F-FNDP specifically labels sEH binding sites in all brain regions studied. Residual binding at highest dose of blocker corresponds to nonspecific binding. CB = cerebellum; Ctx = cortex; Hip = hippocampus; Str = striatum.