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. 2016 Oct 31;7:12849. doi: 10.1038/ncomms12849

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Copyright © 2016, The Author(s)

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(a) The consequences of PARP9 and PARP14 silencing on IFNγ stimulated (TNFα, IL-1β and CCL2/MCP-1) and IL-4 stimulated (MRC1) gene expression in human primary macrophages (n=8). (b) The consequences of PARP9 and PARP14 silencing on IFNγ stimulation (TNFα and iNOS) and IL-4 stimulation (Arg1 and MRC1) gene expression in mouse bone marrow-derived macrophages (n=3). (c) The ratio of phosphorylated STAT1 and STAT6 protein levels to total STAT1 and STAT6 (pSTAT1/tSTAT1 ratio and pSTAT6/tSTAT6 ratio) in human primary macrophages (n=6 and n=5, respectively) of the PARP9 and PARP14 silencing experiments. * P<0.05 and **P<0.01, respectively, by Student's t-test. Error bars indicate s.d.