Table 1. The effect of the added amount of DSPE-PEG on CLA-PTX NPs particle size.
Ratio of weight (w/w) | Z-average Size (nm) | PDI | Size of Peak 1 (nm) | Size of Peak 2 (nm) | Size of Peak 3 (nm) | |
---|---|---|---|---|---|---|
PTX:DSPE-PEG | 1:80 | 118.1 | 0.198 | 2.597 (63.0%) | 23.11 (22.2%) | 161.6 (14.9%) |
1:40 | 241.2 | 0.374 | 2.279 (52.6%) | 382.6 (23.8%) | 24.11 (23.7%) | |
CLA-PTX:DSPE-PEG | 1:80 | 102.40 | 0.216 | 2.664 (60.6%) | 26.50 (20.3%) | 179.8 (19.1%) |
1:40 | 180.10 | 0.283 | 2.304 (45.7%) | 172.9 (31.9%) | 20.79 (22.4%) | |
1:20 | 142.20 | 0.236 | 230.3 (36.4%) | 2.393 (32.6%) | 24.28 (31.0%) | |
1:10 | 441.40 | 0.501 | 101.4 (56.3%) | 2.013 (24.0%) | 16.32 (19.6%) | |
1:7 | 82.23 | 0.163 | 96.44 (100.0%) | |||
1:3 | 90.96 | 0.106 | 101.3 (100.0%) | |||
1:2 | 84.71 | 0.175 | 102.8 (100.0%) | |||
1:1 | 80.20 | 0.184 | 96.80 (100.0%) | |||
1:0.33 | 77.78 | 0.149 | 92.71 (100.0%) | |||
1:0.2 | 88.71 | 0.114 | 101.1 (100.0%) | |||
1:0.15 | 82.67 | 0.095 | 92.62 (100.0%) | |||
1:0.1 | 84.07 | 0.120 | 93.59 (100.0%) | |||
1:0.05 | 76.24 | 0.100 | 84.20 (100.0%) | |||
1:0.025 | 74.38 | 0.120 | 86.01 (100.0%) | |||
1:0.0125 | 72.11 | 0.131 | 84.04 (100.0%) | |||
CLA-PTX NPs | 105.9 | 0.090 | 117.3 (100.0%) |