Table 1. Summary of the different molecules involved in PRL-3 regulation.
Type | Regulator | Function | References |
---|---|---|---|
Transcriptional | P53 | Enhancer | [24] |
TGFβ | Down-regulator | [12] | |
Snail | Enhancer | [26] | |
VEGF | Enhancer | [27] | |
STAT3 | Enhancer | [23] | |
miRNA-495 | Enhancer | [30] | |
Translational | PCBP1 | Down-regulator | [31] |
Posttranslational | TRP32 | Activator | [34] |
Src | Activator | [35] | |
PKC | Predicted phosphorylation | [2] | |
CK2 | Predicted phosphorylation | [2] | |
Farnesyltransferase | Plasma membrane localization | [38] | |
Palmitoyltransferase | Plasma membrane localization | [41] | |
FKBP38 | Proteasome degradation | [43] | |
USP4 | Prevention of degradation | [46] |