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. 2016 Sep 27;473(19):3159–3175. doi: 10.1042/BCJ20160648

Figure 6. Binding of small-molecule kinase inhibitors to PKAc as determined by DSF.

Figure 6.

Thermal stability of WT (A), K72H (B) or R133A (C) PKAc (5 μM) was assessed as a function of inhibitor binding at the indicated concentrations. Mean ΔTm values ± SD (n = 2) are shown.