Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Nov 3;14:74. doi: 10.1186/s12958-016-0206-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 2 — Generation of IL2RG knockout pigs. a An image of IL2RG knockout pigs produced in this study (b) Genotypes of IL2RG knockout female piglets. The dots indicate the deletion mutation in the sequence of IL2RG knockout pigs. c Immunodeficiency presented in IL2RG knockout pigs. The thymic phenotype in IL2RG knockout pigs shows absence of thymus compared to normal thymuses in wild-type pigs. Dotted yellow circle indicates the location of thymus. The histological analysis of the spleens of wild-type and IL2RG knockout pigs indicate that IL2RG knockout pigs lack T and B cells (Original magnification 200×)