Table 2.

Frequencies of mutations and DNA methylation statuses in left‐and right‐sided colorectal cancers with the microsatellite stable phenotype

2‐a
Mutated	Gene	Left‐sided MSS CRCs (%)	Right‐sided MSS CRCs (%)	p‐values
Total		56	15
TP53	positive	33 (58.9)	3 (20.0)	0.006
KRAS	positive	16 (28.6)	11 (73.3)	0.001
BRAF	positive	1 (1.8)	0	NS
PIK3CA	positive	5 (8.9)	1 (6.7)	NS
Chi‐square test

2‐b
		Left‐sided MSS CRCs (%)	Right‐sided MSS CRCs (%)	p‐values
Total		56	15
HME		3 (5.3)	0	NS
IME		28 (50.0)	11 (73.3)
LME		25 (44.7)	4 (26.7)
Chi‐square test

Abbreviations: CRCs: colorectal cancers; HME: high méthylation phenotype; IME: intermediate methylation phenotype; LME: low methylation phenotype.