Table 2.
Paternal and maternal depression and risks of very (≤31 weeks of gestation) and moderately (32–36 weeks of gestation) preterm birth (n = 366 499)
| Very preterm (n = 2194) | Moderately preterm (n = 14 739) | |||||
|---|---|---|---|---|---|---|
| n (%) | OR (95% CI) | n (%) | OR (95% CI) | |||
| Model 1 | Model 2 | Model 1 | Model 2 | |||
| Paternal depression | ||||||
| No depression | 2076 (0.6) | 1.00 | 1.00 | 14 063 (4.0) | 1.00 | 1.00 |
| New depression | 63 (0.9) | 1.43 (1.11–1.85) | 1.38 (1.04–1.83) | 337 (4.8) | 1.16 (1.04–1.30) | 1.12 (1.00–1.26) |
| Recurrent depression | 55 (0.7) | 1.20 (0.91–1.58) | 1.14 (0.84–1.55) | 339 (4.4) | 1.09 (0.98–1.22) | 1.05 (0.94–1.18) |
| Maternal depression | ||||||
| No depression | 1982 (0.6) | 1.00 | 1.00 | 13 250 (3.9) | 1.00 | 1.00 |
| New depression | 103 (0.9) | 1.51 (1.23–1.84) | 1.23 (0.97–1.56) | 598 (5.4) | 1.34 (1.23–1.46) | 1.34 (1.22–1.46) |
| Recurrent depression | 109 (0.7) | 1.19 (0.98–1.44) | 1.11 (0.90–1.38) | 891 (5.9) | 1.47 (1.37–1.58) | 1.42 (1.32–1.53) |
Model 1: adjusted for calendar year of birth, maternal age, parity, paternal education, and paternal age (≥45 years). Model 2: adjusted for the variables listed in model 1, plus smoking, BMI, and also chronological order of parental depression. Note: parental depression was measured in the 12 months before conception up until 24 weeks of gestation. Model 1 is based on 366 499 observations with complete information on the covariates. Model 2 is based on 342 248 observations with complete information on the covariates. Bold numbers represent Wald test P‐values less than 0.05.