Table 1.
Key information affecting computational efficiency for each method
| Methods | Key information affecting computational efficiency |
|---|---|
| Resnik | LCA(t 1,t 2) and IC(LCA(t 1,t 2)) |
| Lin | LCA(t 1,t 2) and IC(LCA(t 1,t 2)) |
| Jiang | LCA(t 1,t 2) and IC(LCA(t 1,t 2)) |
| Pekar | LCA(t 1,t 2) and Dep (LCA(t 1,t 2)) |
| Wang | SV(t 1) and SV(t 2) |
| simUI | A(g 1) and A(g 2) |
| simGIC | A(g 1) and A(g 2) |
For pairwise approaches, we focus on the semantic similarity between t 1 and t 2. For group-wise approaches, the functional similarity between gene g 1 and g 2 requires special attention