Table 1.
Polymer | Mna | Đa | Size (nm)b | ζ-Potential (mV) | # of CANF /nanoparticlec | # of DOTA/nanoparticlec | 64Cu radiolabeling specific activity (GBq/nmol) | Log P |
---|---|---|---|---|---|---|---|---|
Comb | 220,000 | 1.25 | 22 | −35 ± 2 | N/A | 105 | 4.5 ± 0.8 | −2.5 ± 0.3 |
5% CANF-Comb | 166,000 | 1.80 | 17 | 2.6 ± 3.7 | 7 | 105 | 1.4 ± 0.5 | −2.1 ± 0.2 |
10% CANF-Comb | 205,000 | 1.20 | 17 | 1.9 ± 3.4 | 14 | 105 | 5.4 ± 1.2 | −2.0 ± 0.3 |
25% CANF-Comb | 205,000 | 1.20 | 16 | −1.1 ± 1 | 35 | 105 | 3.7 ± 1.1 | −1.3 ± 0.4 |
Determined by GPC in DMF, calibrated to PMMA standards (gmol−1), Đ = Mw/Mn.
Measured by dynamic light scattering.
Predicted incorporation