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. Author manuscript; available in PMC: 2016 Nov 4.
Published in final edited form as: J Pharm Sci. 2008 Dec;97(12):5421–5433. doi: 10.1002/jps.21372

Figure 7.

Figure 7

Effect of Pluronic P85 on the cellular accumulation of saquinavir in MDCKII wild-type and MDR1-transfected cells. Saquinavir accumulation in the MDR1 cells (gray bars) was significantly lower than in the WT cells (black bars). Pluronic P85 significantly increased the accumulation of saquinavir in both WT and MDR1 cells (*p < 0.05). Vinblastine was used as the positive control and Pluronic P85 significantly increased vinblastine accumulation in both WT and MDR1 cells. Results are expressed as mean ± SD (as percentage of wild-type control); n = 9.