Criteria | Definition |
Population | Adult HIV+ patients on ART in Africa |
Interventions | Any intervention to improve adherence to ART |
Comparisons | Standard of care or another intervention to improve adherence to ART |
Outcomes | Any measurement of adherence to ART |
Study Design | RCT with minimum 3 months of follow-up |
Treatment definitions used for categorization of interventions in the network meta-analysis | |
Criteria | Definition |
Standard of Care (SOC) |
Usual standard of care |
Enhanced SOC (eSOC) |
Usual standard of care, plus intensified adherence counseling |
Alarm | Participants received a pocket alarm device which they were to carry around at all times; this device was programmed to beep and flash twice a day to remind patients to take their medication |
eSOC + alarm | Enhanced SOC plus the pocket alarm device as described above |
eSOC + calendar | In addition to enhanced SOC, patients were given a treatment calendar containing educational messages about ART and adherence; patients were to record when they took their medication in the calendar |
Daily SMS | Daily text message sent to the patient’s cell phone (their own or one provided by the study) – with or without ability for patient to respond to care provider |
Weekly SMS | Weekly text message sent to the patient’s cell phone (their own or one provided by the study) – with or without ability for patient to respond to care provider |
eSOC + weekly SMS | Weekly text message sent to the patient’s cell phone (their own or one provided by the study) in addition to enhanced SOC |
eSOC + treatment supporter |
Treatment supporter (chosen by individual or assigned by clinic) in addition to enhanced SOC |
SOC + treatment supporter |
Treatment supporter (chosen by individual or assigned by clinic) in addition to SOC |