Table II. CE-specific T cell response breadth induced by different SIV CE pDNA vaccine regimens.
p27CE pDNA Prime | pDNA Booster Vaccine | Responses to Individual CE | No. of Positive CE per Animal | ||||||
---|---|---|---|---|---|---|---|---|---|
CE1 | CE2 | CE3 | CE4 | CE5 | CE6 | CE7 | |||
T129 | none | + | 1 | ||||||
T136 | none | + | + | + | 3 | ||||
T137 | none | + | + | 2 | |||||
T143 | none | + | + | 2 | |||||
T144 | none | + | + | + | + | 4 | |||
T148 | none | + | 1 | ||||||
T150 | none | + | + | 2 | |||||
T152 | none | + | + | + | 3 | ||||
L986a | none | + | + | 2 | |||||
R108a | none | + | + | 2 | |||||
R677a | none | + | 1 | ||||||
R682a | none | + | + | + | 3 | ||||
R683a | none | + | + | 2 | |||||
R684a | none | + | + | 2 | |||||
L986b | gag | + | + | 2 | |||||
R108b | gag | + | + | 2 | |||||
R677b | gag | + | 1 | ||||||
R682b | gag | + | + | + | 3 | ||||
R683b | gag | + | + | 2 | |||||
R684b | gag | + | + | + | + | 4 | |||
RH01A | CE+gag | + | + | + | + | + | + | 6 | |
RHDE8D | CE+gag | + | + | + | + | 4 | |||
RHDFHW | CE+gag | + | + | + | + | + | + | + | 7 |
RHDN8W | CE+gag | + | + | + | + | + | + | 6 | |
RHFLP | CE+gag | + | + | + | + | + | + | 6 | |
RHOCM | CE+gag | + | + | + | + | + | + | + | 7 |
Analysis of the same animals after CE pDNA prime booster vaccination.
Analysis of the same animals after the gag pDNA booster vaccination.