Table 1.
Subgroup | Stage | Site | Treatment | Patients | Kaplan–Meier survival estimate in % at 24 months | Patients with UW-QOL record | Median (IQR) follow-up in months of UW-QOL record |
---|---|---|---|---|---|---|---|
1 | Early | Oral | Surgery only | 601 | 87 (±1) | 423 | 24 (20–29) |
2 | Early | Pharyngeal | Surgery only | 108 | 88 (±3) | 74 | 22 (18–28) |
3 | Early | Laryngeal | Surgery only | 149 | 88 (±3) | 92 | 25 (20–31) |
4 | Early | Other | Surgery only | 7 | 86 (±13) | 4 | 26* |
5 | Early | Oral | Surgery + RT | 119 | 65 (±4) | 69 | 23 (20–29) |
6 | Early | Pharyngeal | Surgery + RT | 47 | 93 (±4) | 36 | 23 (18–29) |
7 | Early | Laryngeal | Surgery + RT | 31 | 87 (±6) | 17 | 26 (21–33) |
8 | Early | Other | Surgery + RT | 7 | 100 (–) | 5 | 30* |
9 | Early | Oral | RT or CRT | 35 | 40 (±8) | 6 | 36* |
10 | Early | Pharyngeal | RT or CRT | 38 | 63 (±8) | 15 | 21 (17–32) |
11 | Early | Laryngeal | RT or CRT | 115 | 88 (±3) | 58 | 28 (20–43) |
12 | Early | Other | RT or CRT | 11 | 73 (±13) | 6 | 41* |
13 | Late | Oral | Surgery only | 205 | 61 (±3) | 111 | 24 (19–28) |
14 | Late | Pharyngeal | Surgery only | 72 | 73 (±6) | 40 | 21 (17–24) |
15 | Late | Laryngeal | Surgery only | 34 | 76 (±7) | 18 | 27 (19–45) |
16 | Late | Other | Surgery only | 39 | 50 (±8) | 12 | 26 (16–53) |
17 | Late | Oral | Surgery + RT | 334 | 61 (±3) | 182 | 24 (19–28) |
18 | Late | Pharyngeal | Surgery + RT | 197 | 86 (±3) | 145 | 23 (19–28) |
19 | Late | Laryngeal | Surgery + RT | 68 | 73 (±5) | 27 | 25 (21–32) |
20 | Late | Other | Surgery + RT | 72 | 76 (±5) | 45 | 25 (21–31) |
21 | Late | Oral | RT or CRT | 68 | 21 (±5) | 5 | 25* |
22 | Late | Pharyngeal | RT or CRT | 184 | 62 (±4) | 87 | 24 (20–29) |
23 | Late | Laryngeal | RT or CRT | 42 | 46 (±8) | 13 | 21 (14–25) |
24 | Late | Other | RT or CRT | 41 | 57 (±8) | 21 | 25 (18–30) |
Total | 2,624 | 74 (±1) | 1,511 | 24 (20–29) | |||
25 | TOLR | 132 | 89 (±3) | 93 | 24 (19–32) | ||
26 | Laryngectomy | 176 | 72 (±3) | 74 | 32 (25–59) |
UW-QOL = University of Washington Quality of Life; IQR = interquartile range; RT = radiotherapy; CRT = chemoradiotherapy; TORL = transoral laser resection
insufficient cases for computing interquartile range