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. Author manuscript; available in PMC: 2016 Nov 4.
Published in final edited form as: J Immunol. 2014 Jun 4;193(1):412–421. doi: 10.4049/jimmunol.1400055

Figure 8. Enhanced promoter p300 binding, H3K9 acetylation and FasL mRNA expression in alcoholic and non-alcoholic subjects.

Figure 8

Effects of in-vivo alcohol consumption were examined in CD4+ T cells isolated from five non-alcoholic (Control) and five alcoholic (Alcoholic) individuals. ChIP-qPCR was performed using (A) anti p300 antibody or (B) anti acetyl-histone H3 lysine 9 antibodies and primers for region I, II, III and region IV in FasL promoter. Results are represented as mean ± SE (n=5). Statistical analysis was performed by RMME models. P-values:* p < 0.01 compared to control. (C) FasL mRNA levels were determined by real time PCR. Results are represented as mean ± SE (n=5). Statistical analysis was performed by one way ANOVA method. P-values: p < 0.05.