Task 5 (pre-cue delay: 0, 4, 8 s; cue duration: 0.4, 0.8, 1.2 s) percentage of premature responses: (A) Percentage of premature responses as a function of session-block, revealing that the WT Def (p = 0.001) and gt/+ Suf (p = 0.050) groups committed a significantly higher percentage of premature responses than the WT Suf group in session-block 1; and (B) percent premature responses as a function of pre-cue delay; for trials with an 8 s pre-cue delay, the WT Def mice committed a significantly higher percentage of premature responses than WT Suf mice (p = 0.007). Abbreviations: WT Suf: wildtype mice fed a folate sufficient diet; WT Def: wildtype mice fed a folate deficient diet; gt/+ Suf: Mthfd1gt/+ mice fed a folate sufficient diet; gt/+ Def: Mthfd1gt/+ mice fed a folate deficient diet; *indicates significance ≤ 0.05. Data points are means ± SEM.