Table 1. Fathers total body weight, body composition, and blood metabolite profile.
Parameter | CD | HFD | p value |
---|---|---|---|
Total body weights | n = 13 | n = 14 | |
Weight (g) | 28.41 ± 0.75 | 35.46± 0.95 | < 0.0001 |
Adiposity–absolute mass (g) | |||
Perirenal fat (g) | 0.21 ± 0.04 | 0.42 ± 0.04 | 0.0010 |
Retro peritoneal fat (g) | 0.08 ± 0.02 | 0.08 ± 0.03 | NS |
Dorsal fat (g) | 0.36 ± 0.03 | 0.51 ± 0.04 | 0.0100 |
Gonadal fat (g) | 0.88 ± 0.09 | 1.71 ± 0.11 | < 0.0001 |
Omental fat (g) | 0.27 ± 0.03 | 0.56 ± 0.04 | 0.0001 |
Sum of adipose deposits (g) | 1.80 ± 0.18 | 3.27 ± 0.21 | 0.0001 |
Adiposity–relative (% TBW) | |||
Perirenal fat (%) | 0.72 ± 0.12 | 1.19 ± 0.11 | 0.0071 |
Retro peritoneal fat (%) | 0.28 ± 0.08 | 0.21 ± 0.06 | NS |
Dorsal fat (%) | 1.27 ± 0.11 | 1.42 ± 0.10 | NS |
Gonadal fat (%) | 3.06 ± 0.26 | 4.81 ± 0.2178 | 0.0001 |
Omental fat (%) | 0.72 ± 1.19 | 1.19 ± 0.11 | 0.0003 |
Sum of adipose deposits (%) | 6.27 ± 0.48 | 9.19 ± 0.41 | 0.0002 |
Testes weights | |||
Left Testis (g) | 0.08± 0.00 | 0.08 ± 0.00 | NS |
Right Testis (g) | 0.08 ± 0.00 | 0.08 ± 0.00 | NS |
Both Testes (g) | 0.16 ± 0.00 | 0.16 ± 0.00 | NS |
Blood metabolites | |||
Glucose (mmol/L) | 14.11 ± 1.80 | 13.69 ± 1.16 | NS |
Cholesterol (mmol/L) | 4.40 ± 0.62 | 6.48 ± 0.48 | 0.0010 |
Triglyceride (mmol/L) | 1.10 ± 0.14 | 0.98 ± 0.11 | NS |
FFA (mmol/L) | 1.11 ± 0.16 | 1.47 ± 0.12 | 0.0045 |
HDLC3 (mmol/L) | 3.79 ± 0.56 | 5.59 ± 0.43 | 0.0116 |
Insulin (ng ml-1) | 1.71 ± 0.48 | 1.38 ± 0.24 | NS |
Leptin (ng ml-1) | 24.87 ± 3.69 | 27.17 ± 2.98 | NS |
Glucose/Insulin testing | |||
GTT (AUC; mmol.min) | 259 ± 18.6 | 238 ± 30.0 | NS |
ITT (AAC; mmol.min) | 294 ± 23.7 | 276 ± 33.1 | NS |
All data is presented as Mean ± SEM.
CD Control Diet, HFD High Fat Diet, p value determined by 2-tailed t-test, % Weight is expressed as a percent of total body weight, NS Difference between CD/HFD is not significant (P>0.05), TBW total body weight, GTT glucose tolerance test, AUC area under the curve, ITT insulin tolerance test, AAC area above the curve.