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. 2016 Nov 4;11(11):e0165421. doi: 10.1371/journal.pone.0165421

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© 2016 Kerviel et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 7 — A plasmid reverse genetic approach was used to rescue pH1N1 (A/pdm09) carrying M1 WT or M1 R76/77/78A. (A) The viral titers of the rescued viruses were evaluated by plaque assay in MDCK cells. Whereas the wild type virus was rescued (10⁻⁵ dilution), (B) the mutant virus could not be rescued (“neat” virus, no dilution). (C) Virus titers are presented.