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. 2016 Nov 4;11(11):e0165958. doi: 10.1371/journal.pone.0165958

Fig 6. Internal vaginal and uterine phenotype of adult female Gli2+/–;Gli3Δ699/+ mice.

Fig 6

(A-D) Gross external morphology of urogenitalia sinus in female wild type and Gli2+/–;Gli3Δ699/+ mice, blue arrows indicate vaginal opening whereas red arrows indicate anus, and their separation indicates a non-cloacal opening. (E-F) Characteristics of internal reproductive structures, dotted oval indicates the vaginal tube, enlarged in Gli2+/–;Gli3Δ699/+ mice due to double vagina and hypertrophy. (G-H) ink injection assays highlighting the extent of uterine obstruction. (I-J) H&E sectioning of genitalia indicating double vaginas in 30% of Gli2+/–;Gli3Δ699/+ mice (n = 14).