Table 1. Homologous and Heterologous serum NA titer in EV-D68 immunized cotton rats.
| Immunogena | nb | NAc | ||
|---|---|---|---|---|
| ATCC | VANBT | MO/49 | ||
| PBS | 5 | 3.3 ± 0.0d | 3.3 ± 0.0 | 3.3 ± 0.0 |
| UV-VANBT | 15 | 3.3 ± 0.0 | 3.3 ± 0.0 | 3.3 ± 0.0 |
| ATCC | 15 | 8.7 ± 0.5 | 3.5 ± 0.1 | 3.3 ± 0.0 |
| VANBT | 15 | 8.6 ± 0.6 | 13.8 ± 0.3 | 7.2 ± 0.5 |
| MO/49 | 10 | 5.1 ± 0.8 | 6.9 ± 0.8 | 12.7 ± 0.5 |
aFemale cotton rats were immunized i.m. with 106 TCID50/100 μl of indicated virus on day 0 and at 3 weeks. Serum was obtained at 7 weeks.
bNumber of cotton rats used in each vaccination group.
cGeomean ± SE of Log2 NA titers. Highlighted values represent homologous titers.
dLimit of detection of the assay.