Table 2.
Three-month (after the ID) changes in HbA1c, body weight, and systolic blood pressure in type 2 diabetes patients initiating dapagliflozin therapy in primary care practices in Germany
| Variables | N | Baseline ≤6 months before ID | 3 months after ID | Difference (before-after ID) | P-value |
|---|---|---|---|---|---|
| Total patients | |||||
| HbA1c (%) | 826 | 8.5 (1.5) | 7.8 (1.2) | −0.8 (1.4) | <0.001 |
| Body weight (kg) | 268 | 102.7 (22.1) | 100.4 (21.6) | −2.3 (4.8) | <0.001 |
| Systolic blood pressure (mmHg) | 471 | 137.0 (14.5) | 134.8 (17.3) | −2.2 (17.6) | 0.003 |
| Patients treated by general practitioners | |||||
| HbA1c (%) | 682 | 8.6 (1.5) | 7.8 (1.2) | −0.8 (1.4) | <0.001 |
| Body weight (kg) | 180 | 99.7 (22.2) | 97.4 (21.4) | −2.3 (4.9) | <0.001 |
| Systolic blood pressure (mmHg) | 326 | 136.9 (17.4) | 135.1 (17.2) | −1.8 (17.2) | 0.046 |
| Patients treated by diabetologists | |||||
| HbA1c (%) | 144 | 8.4 (1.3) | 7.8 (1.2) | −0.6 (1.3) | <0.001 |
| Body weight (kg) | 88 | 108.9 (20.9) | 106.4 (20.9) | −2.5 (4.8) | <0.001 |
| Systolic blood pressure (mmHg) | 145 | 137.2 (17.7) | 134.2 (17.6) | −3.0 (18.6) | 0.016 |
Note: Data are mean (SD).
Abbreviations: ID, index date; SD, standard deviation; HbA1c, glycated hemoglobin.