Table 3.
Six-month (after the ID) changes in HbA1c, body weight, and systolic blood pressure in type 2 diabetes patients initiating dapagliflozin therapy in primary care practices in Germany
| Variables | N | Baseline ≤6 months before ID | 6 months after ID | Difference (before-after ID) | P-value |
|---|---|---|---|---|---|
| Total patients | |||||
| HbA1c (%) | 645 | 8.5 (1.6) | 7.8 (1.2) | −0.8 (1.5) | <0.001 |
| Body weight (kg) | 239 | 102.3 (22.5) | 99.8 (22.1) | −2.5 (7.1) | <0.001 |
| Systolic blood pressure (mmHg) | 388 | 137.7 (16.7) | 135.4 (16.2) | −2.3 (16.7) | 0.011 |
| Patients treated by general practitioners | |||||
| HbA1c (%) | 530 | 8.5 (1.6) | 7.8 (1.2) | −0.7 (1.5) | <0.001 |
| Body weight (kg) | 167 | 98.9 (21.7) | 96.4 (21.3) | −2.5 (5.4) | <0.001 |
| Systolic blood pressure (mmHg) | 265 | 137.6 (16.9) | 135.7 (16.5) | −2.0 (15.9) | 0.064 |
| Patients treated by diabetologists | |||||
| HbA1c (%) | 115 | 8.6 (1.5) | 7.7 (1.2) | −0.9 (1.3) | <0.001 |
| Body weight (kg) | 72 | 110.1 (22.6) | 107.7 (22.2) | −2.5 (9.9) | 0.031 |
| Systolic blood pressure (mmHg) | 123 | 137.8 (16.4) | 134.8 (15.5) | −2.9 (18.3) | 0.073 |
Note: Data are mean (SD).
Abbreviations: ID, index date; SD, standard deviation; HbA1c, glycated hemoglobin.