Table 2.

Univariate and multivariate survival analyses of overall survival in 181 patients with GC

Parameters	Overall survival
	Univariate		Multivariate
	Mean ± standard error (months)	P-valuea	HR (95% CI)	P-valueb
Age (years)		0.412
<60	36.1±2.8
≥60	31.9±2.8
Gender		0.601
Male	33.9±2.4
Female	35.1±3.7
Histologic grade		0.017		0.047
G1/G2	41.4±4.3		1.000 (reference)
G3	30.0±2.2		1.671 (1.007–2.773)
TNM stage		<0.001		<0.001
I/II	61.8±3.2		1.000 (reference)
III/IV	25.9±1.9		4.230 (2.073–8.632)
Borrmann grouping		<0.001		<0.001
I	28.3±13.7		1.000 (reference)
II	56.7±4.8		0.784 (0.152–4.053)	0.772
III	33.4±2.2		1.612 (0.394–6.597)	0.506
IV	7.9±0.9		8.664 (1.890–39.719)	0.005
Depth of invasion		<0.001
T1/T2	63.3±4.1
T3/T4	30.2±2.0
Lymph node metastasis		<0.001
Negative	56.6±3.9
Positive	29.3±2.1
Liver metastasis		0.010		0.038
Negative	36.1±2.2		1.000 (reference)
Positive	20.9±4.4		1.754 (1.031–2.985)
Peritoneum metastasis		0.376
Negative	34.9±2.4
Positive	32.6±3.7
Tumor size (diameter), cm		<0.001
<5	49.5±3.4
≥5	26.9±2.2
Location		0.589
Upper	36.9±5.5
Middle	29.9±3.9
Lower	35.6±2.6
HABP1 expression		<0.001		0.004
Low	42.8±3.1		1.000 (reference)
High	26.9±2.4		1.730 (1.187–2.522)

Notes:

^aLog-rank test.

^bCox regression test.

Abbreviations: CI, confidence interval; HR, hazard ratio; TNM, tumor, node, and metastasis.