Table 3.
Values for trabecular bone microarchitectural variables at the distal radius in women with type 2 DM and controls without type 2 DM*
| Unadjusted analysis
|
Multivariate-adjusted analysis
|
Holm’s adjusted P | |||||
|---|---|---|---|---|---|---|---|
| Women with type 2 DM (n = 29) | Women without type 2 DM (n = 25) | P | Women with type 2 DM (n = 29) | Women without type 2 DM (n = 25) | P | ||
| Hole size, mm2 | 2.20 ± 0.45 | 1.94 ± 0.33 | 0.011 | 2.22 ± 0.47 | 1.96 ± 0.26 | 0.001† | |
| No. of holes | 72.5 ± 16.9 | 82.9 ± 15.5 | 0.025 | 71.9 ± 17.6 | 81.9 ± 15.8 | 0.022 | 0.154 |
| Endosteal area, mm2 | 310.24 ± 54.98 | 323.33 ± 56.34 | 0.397 | 308.76 ± 56.73 | 322.83 ± 57.87 | 0.319 | 0.957 |
| BVTV, % | 51.2 ± 2.2 | 51.6 ± 1.7 | 0.454 | 51.3 ± 2.1 | 51.5 ± 1.9 | 0.450 | 0.957 |
| Tb.Th, mm | 0.55 ± 0.04 | 0.55 ± 0.02 | 0.591 | 0.56 ± 0.04 | 0.55 ± 0.02 | 0.228 | 0.912 |
| Tb.Sp, mm | 0.92 ± 0.05 | 0.93 ± 0.04 | 0.287 | 0.92 ± 0.06 | 0.93 ± 0.04 | 0.085 | 0.425 |
| Tb.N, mm−1 | 0.53 ± 0.05 | 0.52 ± 0.04 | 0.250 | 0.53 ± 0.05 | 0.52 ± 0.04 | 0.067 | 0.402 |
| Nodal density | 0.69 ± 0.08 | 0.74 ± 0.05 | 0.028 | 0.69 ± 0.08 | 0.73 ± 0.05 | 0.014 | 0.112 |
| Branch density | 0.33 ± 0.03 | 0.33 ± 0.03 | 0.875 | 0.33 ± 0.03 | 0.33 ± 0.02 | 0.776 | 0.957 |
*
Values are the mean ± SD unless indicated otherwise.
DM = diabetes mellitus; BVTV = bone volume fraction; Tb.Th = trabecular thickness; Tb.Sp = trabecular separation; Tb.N = trabecular number.
†
Indicates statistical significance according to Holm’s test for multiple comparisons. Multivariate analysis adjusted for percent body fat, ethnicity, age-adjusted Charlson Index, total daily calcium intake, total daily vitamin D intake, and timed up-and-go test result.