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. 2016 Sep 26;126(11):4103–4118. doi: 10.1172/JCI87492

Figure 8. Manipulation of the actin cytoskeleton reverses actin changes caused by desensitization.

Figure 8

IgE-sensitized serglycin-mCherry (red) RBL-2H3 cells were plated onto covered coverslips and desensitized, then treated with control or 20 μg/ml SptPC481S-TAT for 45 minutes before challenge with Ag for 5 minutes followed by fixation and staining for CD63 (blue) and F-actin (green). Images are representative of 3 independent experiments. Scale bars: 10 μm.