3T3-L1 cells were induced to differentiate in the presence of PF622, URB597, butylparaben (BuP), or benzylparaben (BnP) (1, 10, 50 μM) for 7 days. (A) Parabens dose dependently increase adipocyte differentiation as measured by oil red O while URB597 increases differentiation at 10 μM. (B) Parabens and URB597 increase mRNA expression of the adipocyte markers PPARγ, C/EBPα and FABP4 (n = 3).