Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Inhibition of fatty acid amide hydrolase (FAAH) by parabens and 4-hydroxybenzoate.
| pre-incubation (min) | 5 | 60 |
|---|---|---|
| Compound | IC50 (μM) | |
| URB597 | 0.040 ± 0.011 | 0.0030 ± 0.0005 |
| 4-HO-benzoate | >100 | >100 |
| Methylparaben | >100 | >100 |
| Propylparaben | 9.4 ± 1.0 | 17.1 ± 1.8 |
| Butylparaben | 1.1 ± 0.2 | 2.4 ± 0.5 |
| Benzylparaben | 0.14 ± 0.03 | 0.28 ± 0.03 |
