Table 4.

Treatment, demographic factors and the risk of hypothesized late effects among testicular cancer survivors diagnosed in Utah between 1991 to 2007

	No Eve	Event	Crude HR(95%CI)	Adjusted HR* (95%CI)
Treatment
Radical orchiectomy only	186	48	1.00	1.00
Radical orchiectomy & chemotherapy	83	32	1.33 (0.85,2.08)	1.92 (1.06,3.47)
Radical orchiectomy & radiotherapy	165	64	1.47 (1.01,2.14)	1.04 (0.61,1.78)
Other therapies**	6	4	1.49 (0.54,4.15)	1.6 (0.53,4.88)
Retroperitoneal lymph node dissection
No	344	136	1.00	1.00
Yes	96	12	0.98 (0.54,1.79)	1.17 (0.62,2.23)
Stage
Localized	328	111	1.00	1.00
Regional	72	23	0.96 (0.61,1.51)	1.12 (0.7,1.8)
Advanced	40	14	0.8 (0.46,1.39)	1.01 (0.54,1.88)
Year of diagnosis
1991–1995	74	66	1.00	1.00
1996–2000	137	55	1.08 (0.73,1.6)	0.99 (0.67,1.47)
2001–2005	174	26	1.14 (0.68,1.93)	0.95 (0.54,1.65)
2006–2007	55	1	0.43 (0.06,3.2)	0.33 (0.04,2.63)
Age at cancer diagnosis
<35	307	78	1.00	1.00
35–39	66	27	1.55 (1,2.41)	1.33 (0.85,2.09)
40–44	32	23	2.18 (1.37,3.47)	1.99 (1.23,3.25)
45–49	27	15	2.06 (1.18,3.58)	1.93 (1.09,3.41)
50+	8	5	5.29 (2.12,13.19)	4.39 (1.66,11.67)
Race
White	436	147	1.00	1.00
Non-White	4	1	0.72 (0.1,5.17)	0.55 (0.08,4.04)
BMI
<25 kg/m2	191	37	1.00	1.00
25–29.9 kg/m2	197	77	1.85 (1.25,2.74)	1.65 (1.1,2.47)
30+ kg/m2	52	34	2.88 (1.81,4.61)	2.87 (1.78,4.63)
Marital status
Divorced, widowed, Unmarried	156	49	1.00	1.00
Married	284	99	1.06 (0.75,1.49)	0.98 (0.69,1.39)
Family history of any cancer
No	221	73	1.00	1.00
Yes	219	75	0.84 (0.6,1.15)	0.82 (0.59,1.14)
Family history of testicular cancer
No	428	142	1.00	1.00
Yes	12	6	1.91 (0.84,4.33)	1.81 (0.76, 4.31)

^*Adjusted for age at diagnosis, stage, histology, year of diagnosis, treatment, RPLND where appropriate

^**Unknown, radiotherapy only, chemotherapy only, or radiation+chemotherapy+orchiectomy.