Table 3.
Patient Characteristics |
Overall | GC- HCAP |
GC- CAP |
Non- GC |
GC-HCAP versus GC-CAP (p-value) |
GC-HCAP versus Non- GC (p-value) |
---|---|---|---|---|---|---|
All patients, n | 3,593 | 944 | 808 | 1,841 | ||
Organism identified | 25.6 | 36.4 | 18.9 | 22.9 | <0.0001 | <0.0001 |
Single organism identified |
21.9 | 30.1 | 16.8 | 19.9 | <0.0001 | <0.0001 |
Multiple organisms identified |
3.7 | 6.4 | 2.1 | 3.0 | <0.0001 | <0.0001 |
Culture-positive patients, n |
919 | 344 | 153 | 422 | ||
Gram-positive pathogens |
||||||
S. pneumoniae | 16.4 | 12.2 | 33.3 | 13.7 | <0.0001 | 0.53 |
Streptococcus other |
3.6 | 2.3 | 6.5 | 3.6 | 0.02 | 0.32 |
Staphylococcus aureus |
37.5 | 43.3 | 26.8 | 36.7 | 0.0005 | 0.06 |
Gram-negative pathogens |
||||||
K. pneumoniae | 8.7 | 10.2 | 3.3 | 9.5 | 0.009 | 0.75 |
Pseudomonas | 17.1 | 21.8 | 7.2 | 16.8 | <0.0001 | 0.08 |
H. influenzae | 4.1 | 1.2 | 10.5 | 4.3 | <0.0001 | 0.01 |
E. coli | 3.6 | 5.2 | 1.3 | 3.1 | 0.04 | 0.13 |
Other gram- negatives |
4.6 | 2.9 | 5.9 | 5.5 | 0.11 | 0.08 |
Atypical pathogens | ||||||
Legionella | 1.4 | 1.2 | 2.6 | 1.2 | 0.24 | 0.98 |
Mycoplasma | 0 | 0 | 0 | 0 | -- | -- |
Chlamydia | 0 | 0 | 0 | 0 | -- | -- |
Anaerobes | 0.4 | 0.6 | 0.7 | 0.2 | 0.92 | 0.45 |
GC-HCAP: guideline-concordant healthcare-associated pneumonia
GC-CAP: guideline-concordant community-acquired pneumonia
GC: guideline-concordant