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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: J Crit Care. 2016 Aug 11;36:265–271. doi: 10.1016/j.jcrc.2016.08.004

Table 3.

Bacterial Pathogen Distribution for GC-HCAP, GC-CAP, and Non-GC Patients

Patient
Characteristics
Overall GC-
HCAP
GC-
CAP
Non-
GC
GC-HCAP
versus
GC-CAP
(p-value)
GC-HCAP
versus Non-
GC
(p-value)
All patients, n 3,593 944 808 1,841
  Organism identified 25.6 36.4 18.9 22.9 <0.0001 <0.0001
  Single organism
identified
21.9 30.1 16.8 19.9 <0.0001 <0.0001
  Multiple organisms
identified
3.7 6.4 2.1 3.0 <0.0001 <0.0001
Culture-positive
patients, n
919 344 153 422
  Gram-positive
pathogens
    S. pneumoniae 16.4 12.2 33.3 13.7 <0.0001 0.53
    Streptococcus
other
3.6 2.3 6.5 3.6 0.02 0.32
    Staphylococcus
aureus
37.5 43.3 26.8 36.7 0.0005 0.06
  Gram-negative
pathogens
    K. pneumoniae 8.7 10.2 3.3 9.5 0.009 0.75
    Pseudomonas 17.1 21.8 7.2 16.8 <0.0001 0.08
    H. influenzae 4.1 1.2 10.5 4.3 <0.0001 0.01
    E. coli 3.6 5.2 1.3 3.1 0.04 0.13
    Other gram-
negatives
4.6 2.9 5.9 5.5 0.11 0.08
  Atypical pathogens
    Legionella 1.4 1.2 2.6 1.2 0.24 0.98
    Mycoplasma 0 0 0 0 -- --
    Chlamydia 0 0 0 0 -- --
  Anaerobes 0.4 0.6 0.7 0.2 0.92 0.45

GC-HCAP: guideline-concordant healthcare-associated pneumonia

GC-CAP: guideline-concordant community-acquired pneumonia

GC: guideline-concordant