Table 4.

Selection percentage of each dose combination under the PIPE and waterfall designs. The selection percentages of the true MTDs are shown in boldface.

Sc.	Drug A	Drug B
		Waterfall					PIPE
		1	2	3	4	5	1	2	3	4	5
1	2	21.1	59.8	18.5			56.9	35.2	1.3
	1	0.3	15.5	84.2			0.1	34.5	44.1
2	2	58.5	18.7	1.0			41.1	3.0	0.0
	1	18.2	55.9	25.5			30.5	42.6	5.1
3	2	53.6	19.7	2.8			37.9	6.3	0.4
	1	6.5	28.8	64.5			9.2	49.3	33.0
4	2	23.4	5.9	0.3			10.7	0.5	0.0
	1	56.5	24.4	6.9			44.5	13.5	1.2
5	4	9.6	1.6	0.0	0.0		9.6	0.8	0.0	0.0
	3	60.1	15.5	1.2	0.0		37.2	18.1	1.5	0.0
	2	20.6	54.1	23.1	1.3		15.2	39.0	9.8	1.3
	1	9.7	15.8	54.3	20.2		0.1	13.8	42.0	8.8
6	4	66.4	7.7	0.0	0.0		42.6	2.2	0.0	0.0
	3	20.3	65.2	13.0	0.2		24.6	45.1	2.3	0.0
	2	9.6	13.1	66.4	10.8		0.2	21.7	52.4	1.9
	1	8.8	0.8	15.6	74.8		0.0	0.0	22.2	46.6
7	4	1.1	0.0	0.0	0.0		5.7	0.4	0.0	0.0
	3	13.6	0.5	0.2	0.0		15.7	4.4	0.4	0.0
	2	67.2	15.7	1.5	0.0		30.4	19.6	2.8	0.5
	1	14.3	56.3	26.7	2.7		12.1	31.3	20.7	4.4
8	4	1.3	0.1	0.0	0.0		7.2	1.0	0.0	0.0
	3	17.4	0.8	0.1	0.0		19.2	6.1	1.7	0.0
	2	69.1	15.2	1.6	0.2		26.4	21.0	9.5	2.7
	1	8.3	2.4	32.9	56.4		0.1	4.8	36.8	47.1
9	3	1.6	21.7	61.4	15.1	0.0	3.2	51.3	40.3	4.2	0.1
	2	0.0	0.3	17.5	67.1	15.1	0.0	0.0	27.1	45.6	3.7
	1	0.0	0.0	0.8	19.8	79.4	0.0	0.0	0.2	23.7	45.0
10	3	20.0	65.9	12.8	0.1	0.0	47.1	44.0	5.4	0.4	0.0
	2	1.1	13.6	67.3	17.3	0.7	0.1	20.7	49.4	8.1	0.2
	1	0.1	0.1	0.6	22.1	77.1	0.0	0.0	2.1	47.1	42.1
11	3	69.6	17.5	0.8	0.0	0.0	48.9	10.0	0.9	0.0	0.0
	2	1.5	20.3	62.3	14.7	1.2	1.3	43.4	42.7	6.3	0.7
	1	0.2	0.0	1.1	22.1	76.6	0.0	0.0	2.5	44.6	46.5
12	3	14.7	2.1	0.2	0.0	0.0	15.7	5.3	0.4	0.0	0.0
	2	64.8	20.1	2.1	0.2	0.0	29.4	19.3	6.9	1.7	0.2
	1	4.7	14.5	54.7	21.8	4.3	0.0	29.7	34.9	17.3	6.5
13	3	12.0	0.7	0.0	0.0	0.0	13.3	3.3	0.6	0.0	0.0
	2	69.5	15.1	1.8	0.1	0.0	31.8	21.6	6.9	2.5	0.1
	1	4.8	1.0	26.8	45.9	21.5	0.0	6.3	33.3	41.2	15.1
14	3	13.3	1.1	0.0	0.0	0.0	12.2	1.8	0.0	0.0	0.0
	2	63.8	15.8	0.9	0.0	0.0	35.5	15.8	4.0	0.3	0.0
	1	16.7	61.5	19.9	1.7	0.2	15.5	34.8	16.3	6.5	0.4