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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Pharm Res. 2016 Sep 12;33(12):2954–2966. doi: 10.1007/s11095-016-2017-y

Figure 4.

Figure 4

Timeline of pharmacokinetic studies. An osmotic pump delivered 3.2 mg/kg/day of METH throughout the course of the study. Prior to administration of the therapeutic protein dose, a blood sample was taken to establish a baseline. ScFv7F9Cys-PEG20K was administered on day 0. Blood samples were taken at 1, 5, 10, 30 mins, 1, 2, 4, 8, 24, 48, 72, and 96 hrs after the protein dose administration. Animals were sacrificed on day 4 of the study.