Table 2.

Local maxima of increased volume in ET patients with head tremor compared to ET patients without head tremor and local maxima of reduced volume in FCMTE compared to ET and controls

Region	Hemisphere	t Value	P FWE-corr	Cluster size	x, y, z in mm
Study 1—ET head tremor > ET no head tremor
Postcentral gyrus	Right	6.07	0.002	1396	59	−4	28
Precentral gyrus	Right	5.16			44	17	34
Precentral gyrus	Right	4.96			51	11	33
Superior medial gyrus	Right	5.43	0.016	857	6	54	36
Superior medial gyrus	Right	4.08			2	42	33
Superior medial gyrus	Right	3.99			3	42	42
Postcentral gyrus	Left	5.39	0.001	1414	−60	−3	28
Precentral gyrus	Left	4.74			−50	6	39
Precentral gyrus	Left	4.44			−48	11	31
Study 2—ET > FCMTE
Cerebellum crus II	Left	5.37	0.005	1160	−25	−77	−42
Cerebellum lobule VI	Left	4.75			−23	−62	−31
Cerebellum crus I	Left	4.53			−34	−50	−35
Study 2—controls > FCMTE
Cerebellum lobule VIIIa	Right	6.11	<0.001	4522	12	−67	−42
Cerebellum crus I	Right	5.41			25	−74	−34
Cerebellum lobule V	Right	5.33			14	−51	−18
Cerebellum crus I	Left	5.45	<0.001	3188	−20	−74	−33
Cerebellum lobule VI	Left	4.91			−18	−64	−27
Cerebellum crus I	Left	4.70			−37	−49	−36
Cerebellum lobule IX	Left	5.30	<0.001	3133	−14	−46	−48
Cerebellum lobule VIIIb	Left	4.97			−16	−60	−47
Cerebellum lobule X	Left	4.59			−21	−43	−45
Cerebellum lobule IX	Right	5.27	0.01	990	8	−55	−52
Cerebellum lobule VIIIb	Right	4.92			5	−62	−39
Cerebellum lobule IX	Right	4.47			6	−49	−43

Stereotactic coordinates of the local maxima of clusters showing volume reduction in FCMTE compared to ET and controls (cluster-wise inference was used (P < 0.05 (FWE corrected), cluster-forming threshold P < 0.001). Cluster size is given in number of voxels. MNI stereotactic coordinates for cortical regions, SUIT coordinates for infratentorial regions