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. 2016 Mar 22;266(8):725–736. doi: 10.1007/s00406-016-0684-7

Table 3.

DSM-IV research criteria for mixed anxiety depressive disorder [19]

Persistent or recurrent dysphoric mood for at least 1 month
The dysphoric mood is accompanied by at least 1 month of four (or more) of the following symptoms
 Difficulty concentrating or mind going blank
 Sleep disturbance (difficulty falling asleep or staying asleep, or restless unsatisfying sleep)
 Fatigue or low energy
 Irritability
 Worry
 Being easily moved to tears
 Hypervigilance
 Anticipating the worst
 Hopelessness
 Low self-esteem or feelings of worthlessness
The symptoms cause clinically significant distress or impairment in social, occupational, or other important areas of functioning
The symptoms are not a result of the direct physiological effects of a substance or a general medical condition
All of the following
 Criteria have never been met for major depressive disorder, dysthymic disorder, panic disorder, or GAD
 Criteria are not currently met for any other anxiety or mood disorder (including an anxiety or mood disorder in partial remission)
 The symptoms are not better accounted for by any other mental disorder