Table 1.
Characteristics of HIV-1-infected former plasma donors (FPDs) and control individuals
| Characteristics | HIV-1-monoinfected | HIV-1/HCV-coinfected | Healthy |
|---|---|---|---|
| Number | 40 | 36 | 36 |
| Female* | 25 (62.5) | 20 (55.6) | 18 (50.0) |
| Age (years)† | 43 (9.4) | 44 (9.3) | 46 (10.2) |
| Deduced infection time (years)† | 15.1 (1.5) | 14.8 (1.5) | NAa |
| Clinical data | |||
| ALT (IU/L)†b | 22.5 (25.1) | 33.0 (50.5) | 19 (12.0) |
| AST (IU/L)†c | 29.0 (24.9) | 35.5 (57.5) | 22 (11.6) |
| HIV-status | |||
| Anti-HIV | Positive | Positive | NA |
| HIV RNA (copies/ml)† | 11,452 (8933) | 11,075 (7866) | NA |
| CD4 cells/μl† | 384 (234) | 403 (233) | NA |
| CD8 cells/μl† | 936 (394) | 850 (517) | NA |
| HCV-status | |||
| Anti-HCV | Negative | Positive | NA |
| HCV RNA (log10 IU/ml)† | 0 (0) | 6.4 (0.9) | NA |
| HCV genotype | |||
| 1b* | NA | 15 (41.7) | NA |
| 2a* | NA | 20 (55.6) | NA |
| Others* | NA | 1 (2.7) | NA |
* Number of cases (number/total in %)
† Mean ± standard deviation (SD)
aNot applicable, b alanine aminotransferase, c aspartate aminotransferase