Table 3.

Clinical characteristics related to seizure recurrence after early onset post-ischemic stroke seizure

Clinical characteristics	Not recurred	Recurred	Univariable analysis		Multivariable analysis
	(N = 31)	(N = 17)	p-value	OR (95 % CI)	p-value	OR (95 % CI)
Age (years old)	65.7 ± 14.9	66.1 ± 12.6	0.941		0.882a	0.880 (0.161–4.799)
Male gender	17 (54.8 %)	12 (70.6 %)	0.286	1.976 (0.560–6.971)	0.033*	11.822 (1.222–114.347)
Diabetes mellitus	16 (51.6 %)	4 (23.5 %)	0.059	0.288 (0.077–1.084)	0.347	0.346 (0.038–3.167)
Hypertension	23 (74.2 %)	10 (58.8 %)	0.272	0.497 (0.141–1.747)	0.355	0.353 (0.039–3.206)
Atrial fibrillation	3 (9.7 %)	5 (29.4 %)	0.112	3.889 (0.799–18.938)	0.106	10.451 (0.609–179.306)
Lesion size
Small	4 (12.9 %)	3 (17.6 %)			0.360
Moderate	13 (41.9 %)	4 (23.5 %)			0.576	2.779 (0.077–99.920)
Large	14 (45.2 %)	10 (58.8 %)	0.468		0.440	0.412 (0.043–3.910)
Cortical involvement	21 (67.7 %)	14 (82.4 %)	0.330	2.222 (0.518–9.537)	0.163	6.406 (0.471–87.078)
Hemorrhagic transformation	6 (19.4 %)	2 (11.8 %)	0.694	0.556 (0.099–3.114)	0.197	0.155 (0.009–2.632)
Functional disability
Mild	12 (38.7 %)	4 (23.5 %)			0.402
Moderate	4 (12.9 %)	2 (11.8 %)			0.564	0.386 (0.015–9.788)
Severe	15 (48.4 %)	11 (64.7 %)	0.532		0.293	3.517 (0.349–32.620)
Status epilepticus	8 (25.8 %)	5 (29.4 %)	1.000	1.198 (0.321–4.473)	0.941	1.077 (0.151–7.673)
Relevant EEG findings (N = 45)	17 (54.8 %)	10 (58.8 %)	0.900	0.924 (0.271–3.156)	0.951	1.067 (0.134–8.512)
Partial seizure type	14 (45.2 %)	11 (64.7 %)	0.195	2.226 (0.657–7.545)	0.159	4.619 (0.546–38.873)

OR odds ratio, CI confidence interval, EEG electroencephalography

Statistical significance with p < 0.05*

^a Variables were substituted whether patients were younger than 65 years old