Table 4.

Clinical characteristics related to seizure recurrence after late onset of post-ischemic stroke seizure

Clinical characteristics	Not recurred	Recurred	Univariable analysis		Multivariable analysis
	(N = 39)	(N = 37)	p-value	OR (95 % CI)	p-value	OR (95 % CI)
Age (years old)	70.7 ± 9.1	62.7 ± 11.9	0.001**		0.050*a	3.746 (1.000–14.040)
Male gender	14 (35.9 %)	26 (70.3 %)	0.003**	4.221 (1.613–11.043)	0.027*	4.552 (1.183–17.511)
Diabetes mellitus	14 (35.9 %)	10 (27.0 %)	0.406	0.661 (0.249–1.757)	0.460	0.578 (0.135–2.476)
Hypertension	31 (79.5 %)	25 (67.6 %)	0.238	0.538 (0.190–1.518)	0.451	0.566 (0.129–2.488)
Atrial fibrillation	16 (41.0 %)	12 (32.4 %)	0.438	0.690 (0.270–1.764)	0.521	0.647 (0.171–2.443)
Lesion size
Small	2 (5.1 %)	1 (2.7 %)			0.581
Moderate	8 (20.5 %)	6 (16.2 %)			0.999	-
Large	29 (74.4 %)	30 (81.1 %)	0.520		0.298	0.329 (0.041–2.667)
Cortical involvement	37 (94.9 %)	34 (91.9 %)	0.671	0.613 (0.096–3.891)	0.999	-
Hemorrhagic transformation	7 (17.9 %)	13 (35.1 %)	0.089	2.476 (0.858–7.150)	0.688	1.370 (0.296–6.347)
Functional disability
Mild	5 (12.8 %)	7 (18.9 %)			0.802
Moderate	15 (38.5 %)	14 (37.8 %)			0.854	1.216 (0.151–9.796)
Severe	19 (48.7 %)	16 (43.2 %)	0.490		0.558	1.833 (0.205–16.406)
Status epilepticus	14 (35.9 %)	6 (16.2 %)	0.051*	0.346 (0.116–1.030)	0.057	0.208 (0.041–1.048)
Relevant EEG findings (N = 71)	30 (76.9 %)	22 (59.5 %)	0.051*	0.338 (0.111–1.030)	0.118	0.294 (0.063–1.367)
Partial seizure type	14 (35.9 %)	17 (45.9 %)	0.373	1.518 (0.605–3.808)	0.237	2.227 (0.590–8.404)

OR odd ratio, CI confidence interval, EEG electroencephalography

Statistical significance with p < 0.05* and p < 0.01**

^a Variables were substituted whether patients were younger than 65 years