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. 2016 Nov 4;9:49. doi: 10.1186/s13072-016-0100-6

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Read coverage across the genome. Images of tiled data files (TDFs) generated by the IGV browser [34, 35] displaying the density tracks of reads aligned across the genome. The tracks show the correspondence in read coverage in monoclonal and polyclonal antibodies over representative genomic loci. a Chromosome 7: 44,829,782–44,930,648 (about 100 kb), shows the read coverage of histone modifications associated with “active chromatin” (H3K4me1, H3K4me3 and H3K27ac). The correspondence of read coverage of datasets for two major histone modifications associated with repression: b H3K27me3 [chromosome 22:19,492,023–19,849,594 (about 350 kb)] and c H3K9me3 [chromosome 19: 51,746,058–53,362,194 (about 1.6 Mb)]