Fig. 4.

Correlation between monoclonal and polyclonal antibodies across the genome. Scatter plots (Loglog) presenting counts of reads per bin in non-overlapping 2000-bp windows tiled throughout the genome in replicates of the monoclonal antibody (left; gray), the polyclonal antibody (right; gray) and polyclonal versus monoclonal (center; blue). The H3K27me3 data (a), show that the reproducibility is nearly indistinguishable from the reproducibility of data derived from technical replicates using the same antibody, while the H3K27ac data (b) show divergence between polyclonal and monoclonal antibodies