Table 3.

Sensitivity and specificity data for histone modifications associated with open chromatin

	Specificity		Sensitivity
	Mono (%)	Poly (%)	Mono (%)	Poly (%)
H3K27ac	89	85	68	69
H3K4me1	38	36	54	59
H3K4me3	91	90	86	87

Sensitivity and specificity of monoclonal and polyclonal antibodies. Specificity is calculated as the percentage of the genomic bases that are identified as peaks that are within the expected canonical genomic region, as annotated by ENCODE. Sensitivity is calculated at the percentage of bases within the expected genomic region that are identified as being within peaks. Only genomic bases annotated in the ENCODE segmentation tracks for K562 are included in this calculation